Preclinical Work

This module deals with underlying mechanisms of Brain Stimulation action (TMS, tDCS, DBS) in behavioral paradigms and pathological variants (Klaus Funke, Bochum; Christine Winter, Dresden; clinical translation: Thomas Schläpfer, Bonn).

Beside identifying mechanisms of action (neurotransmission, transcriptional factors, electrophysiology) this module investigates whether Brain Stimulation effects depend on functional states in normal behavior and pathological situations (state-dependency). Finally, it serves to identify relevant parameters for further developing Brain Stimulation methods (enhanced therapy).