Preclinical Work

This module focuses on cortex physiology of tDCS and TMS, as well as state-dependent stimulation in humans.

Three fields will be covered:

  1. The dynamics of brain stimulation effects and their state-dependency with regard to pharmacological interventions (Michael Nitsche, Dortmund).
  2. Disorder-directed development of Brain Stimulation using comparative fMRI studies in healthy subjects and in two pathological conditions, i.e. major depression and anticipatory anxiety in specific phobia (Frank Padberg, Munich).
  3. Modulation of cognitive control using Brain Stimulation (Christian Plewnia, Andreas Fallgatter, Tübingen).                   

In addition, all workpackages of this module allow improving current brain stimulation approaches towards enhanced treatment strategies leading to further PoP or PoE trials.